Which phase of the ventricular action potential corresponds to rapid Na+ influx?

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Multiple Choice

Which phase of the ventricular action potential corresponds to rapid Na+ influx?

Explanation:
The rapid Na+ influx occurs during Phase 0, the upstroke depolarization. In ventricular myocytes, fast voltage-gated Na+ channels open quickly in response to the initial depolarization, allowing a large influx of sodium ions which drives a sharp, steep rise in membrane potential. Phase 1 is the brief initial repolarization from a transient outward K+ current. Phase 2 is the plateau stage where Ca2+ enters the cell through L-type channels, balancing K+ efflux to sustain depolarization. Phase 3 is repolarization driven by continued K+ efflux returning the cell to its resting potential. Phase 0 is specifically the phase that features rapid Na+ influx.

The rapid Na+ influx occurs during Phase 0, the upstroke depolarization. In ventricular myocytes, fast voltage-gated Na+ channels open quickly in response to the initial depolarization, allowing a large influx of sodium ions which drives a sharp, steep rise in membrane potential.

Phase 1 is the brief initial repolarization from a transient outward K+ current. Phase 2 is the plateau stage where Ca2+ enters the cell through L-type channels, balancing K+ efflux to sustain depolarization. Phase 3 is repolarization driven by continued K+ efflux returning the cell to its resting potential. Phase 0 is specifically the phase that features rapid Na+ influx.

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